Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today. 

City of Hope is seeking experienced Nurse Managers to lead operations and clinical teams across multiple specialty areas. This is an exciting opportunity for leaders who excel in staff development, patient-centered care, and operational management.

About the Role

The Nurse Manager oversees daily operations and program management for a designated group of clinics or units, collaborating closely with the Director of Nursing. Responsible for achieving financial, quality, and strategic goals, the Nurse Manager leads with a positive, people-focused approach, fostering a supportive and engaging work environment. Acting as a change agent, they promote open communication, professional development, and adherence to regulatory and organizational standards while ensuring efficient use of resources and the delivery of safe, high-quality patient care.

Primary Responsibilities

• Lead, mentor, and support nursing staff to deliver safe, high-quality, patient-centered care.

• Oversee daily operations and ensure efficient staffing and resource allocation.

• Manage budgets and monitor financial performance.

• Guide quality improvement initiatives and maintain regulatory compliance.

• Foster professional development, engagement, and a positive workplace culture.

• Collaborate with interdisciplinary teams to achieve organizational and patient care goals.

• Act as a change agent, promoting innovation and continuous improvement.

Where We Are Hiring

• We have Manager opportunities across multiple clinical service lines, such as:

• Inpatient Oncology

• Outpatient Oncology

• Evaluation Treatment Center

• Infusion

• Perioperative Services

Your qualifications should include: 

• Education: BSN or MSN.

• Experience: At least 3 years of experience in an area of expertise relevant to the department with demonstrated progressive leadership growth.

• Licensure: Current California RN license (or ability to obtain within 6 months), BLS certification, and national certification in area of expertise or leadership (within 12 months), ACLS or PALS based on selected department.

Who Thrives Here

You are a leader who:

• Thinks strategically and acts with clarity and purpose.

• Promotes professionalism, accountability, and teamwork.

• Supports staff in developing confidence, expertise, and curiosity.

• Balances empathy and high expectations.

• Drives improvement—while modeling patience, presence, and respect.

Ready to lead in a place where nursing excellence is valued and supported?

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.