Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

City of Hope is undergoing a transformative evolution of its commercialization and strategic partnerships organization to accelerate the translation of scientific innovation into impactful solutions for patients. As part of this evolution, we are building an integrated, externally facing commercial engine across business development, venture creation, strategic partnerships, and innovation ecosystem development.

The Chief of Staff will serve as a strategic and operational partner to the Chief Commercialization Officer, supporting enterprise-wide initiatives, driving operational execution, enabling cross-functional alignment, and enhancing organizational effectiveness. This highly visible leadership role will help drive execution against key priorities, coordinate complex initiatives, and support leadership decision-making across a highly matrixed environment.

As a successful candidate, you will:

• Partner closely with the Chief Commercialization Officer as a strategic advisor across the commercial organization
• Drive execution of strategic priorities and transformation initiatives
• Coordinate cross-functional efforts across business development, licensing, partnerships, and venture activities
• Lead complex, enterprise-wide projects involving multiple stakeholders
• Develop executive-level presentations, board materials, and strategic communications
• Establish and manage operating rhythms, governance processes, and leadership forums
• Track KPIs, milestones, and organizational performance metrics to ensure accountability
• Identify operational gaps, risks, and opportunities, and drive solutions proactively
• Serve as a key liaison across leadership, scientific stakeholders, and external partners
• Support organizational design, process optimization, and scaling initiatives

Your qualifications should include:

• Bachelor’s degree required; MBA or other advanced degree preferred
• 10+ years of experience supporting C-suite leadership in commercialization, strategy, R&D, or related functions
• 7+ years of experience leading senior teams and driving complex initiatives
• Executive-level communication skills with the ability to develop high-impact presentations and materials
• Proven ability to manage cross-functional projects in highly matrixed environments
• Strong organizational, strategic thinking, and project management capabilities
• Demonstrated ability to influence senior stakeholders and drive alignment
• Experience in process improvement, operational scaling, and performance tracking
• High level of discretion, business acumen, and interpersonal effectiveness
• Financial acumen, including experience with budgets and business modeling

City of Hope employees’ pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.