Join the forefront of groundbreaking research at City of Hope where our mission is to transform the future of cancer care through precision medicine and innovative immuno-oncology. We are seeking a highly motivated and hands-on Research Associate II to support laboratory-based research on colorectal cancer immunotherapy and tumor microenvironment biology.

This position is ideal for a candidate eager to gain advanced experience in spatial and single-cell technologies, clinical translational research, and biomarker discovery. The successful candidate will work closely with Dr. Marwan Fakih and Dr. Jian Ye, contributing directly to ongoing clinical-correlative studies and mechanistic projects using cutting-edge techniques.

You will be part of a translational research team tackling immunotherapy resistance in colorectal cancer, using state-of-the-art spatial and molecular platforms. This position provides an exceptional opportunity to develop hands-on skills in both clinical sample handling and cutting-edge research technologies, with publication opportunities.

As a successful candidate, you will:

• Perform wet-lab and technical experimental work related to translational immuno-oncology studies in colorectal cancer.

• Process and manage clinical biospecimens (tumor tissues, blood, and FFPE samples) for downstream molecular and spatial analyses.

• Conduct advanced spatial biology and immunology assays.

• Maintain organized sample inventory, records, and reagent tracking.

• Assist with basic data analysis, figure preparation, and presentation of results.

• Collaborate with clinicians and scientists to integrate molecular and imaging data for mechanistic and biomarker discovery studies.

• Contribute to the preparation of research reports, manuscripts, and grant applications.

Your qualifications should include:

• Bachelor’s degree in Biology, Molecular Biology, Immunology ore related field. Master’s degree preferred.

• Two years related research/ laboratory experience with a Bachelor’s degree or one year related research/ laboratory experience with a Master’s degree.

Preferred qualifications:

• Prior experience with immunohistochemistry, flow cytometry, or molecular biology techniques is strongly preferred.

• Experience with spatial transcriptomics, multiplex imaging, or single-cell technologies is a plus but not required.

• Strong motivation to learn and contribute to both clinical and basic cancer research.

• Ideal for candidates interested in pursuing future graduate, medical, or academic research careers.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.